WebFeb 23, 2011 · Most proteomic efforts can be grouped into several distinct categories: (1) cataloging the spectrum of proteins that comprise the normal, resting (quiescent) platelet proteome, (2)... WebFeb 8, 2024 · Ser24 phosphorylation and proteolytic cleavage of Dab2 during agonist-induced human platelet activation. a The Dab2 Ser24 phospho-peptide (P-pep) but not the non-phospho-peptide (NP-pep) was recognized by a dot blot assay using the anti-p-Dab2 (S24) antibody. b 293T cells were transfected with HA-Dab2 (S24) or HA-Dab2-S24A …
Integrin αIIbβ3 outside-in signaling activates human platelets through …
WebApr 12, 2024 · Spindle-shaped platelets contained a small number of granules and did not exhibit active adhesion, while the structure of their membranes was normal after 1-2 days of storage and abnormalities appeared during subsequent storage. Morphofunctional properties of spindle-shaped platelets under normal and pathological conditions were … WebJul 9, 2024 · In our previous work, we have used protein mass spectrometry techniques for quantitative analysis of the global platelet proteome 18 and of the iloprost-induced platelet phosphoproteome 19. In the ... flowergate whitby
Proteomic and Phospho-Proteomic Profile of Human Platelets in …
WebNov 5, 2024 · The Phosphoproteomic Analysis Identified More Than 1500 Phosphosites We analyzed the phosphoproteome of equivalent amounts of protein extracted from isolated resting platelets from 12 obese patients (4 pools of 3 individuals each) and 12 age- and gender-matched lean controls by liquid chromatography-mass spectrometry-tandem … WebJul 9, 2003 · In resting platelets two distinct signals (spots A and B) were detected. A thrombin stimulation caused the incidence of two additional spots (C and D) slightly … WebOct 1, 2016 · These lists contain considerable overlap with the phosphoproteome changes reported for human platelets activated with thrombin or oxidized phospholipids (16). … flowergate apartments metairie la