Incidence of rhabdomyolysis with daptomycin

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August undefined, 2024

WebNov 17, 2024 · However, the risk of developing rhabdomyolysis from statin therapy is very low, around 1.5 for each 100,000 people taking statins. Rhabdomyolysis or milder forms … WebDec 11, 2024 · Daptomycin is associated with an increased incidence of myopathy and rhabdomyolysis. There have been cases reported in patients with and without acute renal …

Safety outcomes with high‐dose daptomycin in patients with acute kidney …

WebApr 16, 2024 · Background: Daptomycin-associated myopathy has been identified in 2-14% of patients, and rhabdomyolysis is a known adverse effect. Although risk factors for daptomycin-associated myopathy are... WebTo determine the incidence and characteristics of significant adverse effects in patients receiving high-dose daptomycin with severe renal dysfunction. ... One patient experienced significant CK elevation while on daptomycin therapy with rhabdomyolysis; however, daptomycin was continued as there was an alternative explanation for an elevated CK ... chuck and buck imdb

Effect of Statin Coadministration on the Risk of …

WebThe incidence of myopathy and rhabdomyolysis were highest during the first year and then decreased during the subsequent years of treatment. In another clinical outcomes study … WebJun 15, 2006 · Abstract. The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. … WebMay 18, 2024 · Daptomycin is the antibiotic most strongly associated with rhabdomyolysis, with rhabdomyolysis cases totaling 5.5% of daptomycin reports to FAERS, the FDA Adverse Event Reporting System. ... It has been suggested that decreased perioperative fluid administration may decrease the incidence of rhabdomyolysis in the bariatric surgery … chuck and burnie\u0027s deer processing

Daptomycin (Intravenous Route) Side Effects - Mayo Clinic

WebMar 19, 2024 · The meta-analysis found that statin use significantly increased the incidence of DAP-related rhabdomyolysis compared with no statin use (6.2% vs 13.0%; odds ratio [OR] 3.83; 95% CI 1.43, 10.26) but had no significant effect on the incidence of DAP-related myopathy (6.6% vs 6.0%). WebRhabdomyolysis has been reported in up to 5 percent of treated patients receiving daptomycin . Factors conferring increased risk for daptomycin-associated myopathy or rhabdomyolysis include : … Overview of the causes and treatment of hyperphosphatemia … designer shoe warehouse mentor ohioWebRhabdomyolysis is a known possible complication associated with daptomycin therapy. However, previous findings were predominantly in phase 1 and 2 trials, and the effects … designer shoe warehouse montgomery al

"WebSep 29, 2024 · Introduction. Daptomycin is a lipopeptide antibiotic often used for the treatment of methicillin-resistant Staphylococcus aureus (MRSA). Despite its clinical utility, there have been a few reports of rhabdomyolysis related to daptomycin use [1,2].In this report, we present a case of rhabdomyolysis, severe hyperkalemia, and acute kidney injury … " - Incidence of rhabdomyolysis with daptomycin

Incidence of rhabdomyolysis with daptomycin

A case report and literature review of daptomycin-induced liver …

WebThe incidence of myopathy and rhabdomyolysis were highest during the first year and then decreased during the subsequent years of treatment. In another clinical outcomes study in which 10,269 adult patients were treated with simvastatin 40 mg per day (mean follow-up of 5 years), the incidence of myopathy/rhabdomyolysis was <0.1% in patients ... WebMar 21, 2024 · Incidence not known Diarrhea, watery, and severe, which may also be bloody dry cough puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue stomach cramps or tenderness Other side effects of Daptomycin Some side effects of daptomycin may occur that usually do not need medical attention.

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WebDaptomycin has been associated with raised creatine kinase activity, with a reported incidence of 2.8% in phase III clinical trials (167 A). Rhabdomyolysis has also been described (168 A ) . A 45-year-old woman with refractory acute myeloid leukemia was given intravenous daptomycin 550 mg (6 mg/kg) every 24 hours because of bacteremia due to ... WebWe have encountered numerous cases of rhabdomyolysis associated with acute pesticide intoxication; however, the cause, incidence, and treatment outcomes of rhabdomyolysis …

WebJan 16, 2024 · Rhabdomyolysis means dissolution of skeletal muscle, and it is characterized by leakage of muscle cell contents, myoglobin, sarcoplasmic proteins (creatine kinase, lactate dehydrogenase, aldolase, … WebRhabdomyolysis is a well-known clinical syndrome of muscle injury associated with myoglobinuria, electrolyte abnormalities, and often acute kidney injury (AKI). The pathophysiology involves injury to the myocyte membrane and/or altered energy production that results in increased intracellular calcium concentrations and initiation of destructive …

WebDaptomycin is reported to cause an elevation in creatine kinase levels, although frank rhabdomyolysis is rare. An even more infrequent occurrence is the simultaneous development of acute kidney injury and drug-induced liver injury with rhabdomyolysis. Daptomycin and rifampin combination are used for synergistic bactericidal action against … Webin patients placed on Daptomycin due to increased risk of rhabdomyolysis. Infections due to fungi, mycobacteria, or Actinomyces require longer durations of therapy – consult …

WebMar 7, 2024 · INTRODUCTION. Daptomycin is a lipopeptide antimicrobial with activity against gram-positive organisms, including antimicrobial-resistant pathogens such as …

WebJun 15, 2006 · The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. … chuck and bob soapWebEarly-onset rhabdomyolysis related to daptomycin use. Early-onset rhabdomyolysis related to daptomycin use Int J Antimicrob Agents. 2007 Nov;30(5):472-4. doi: … chuck and charlie morrisWebNov 23, 2024 · Citation 8 In contrast, a study by Graham et al Citation 9 in 2004 reported an average incidence of 0.44 in 10,000 patients (who developed rhabdomyolysis) being treated with atorvastatin, simvastatin, or pravastatin, with a 95% confidence interval of 0.20–0.84. These patients had been taking lipid-lowering agents alone or in combination. designer shoe warehouse morrisvilleWebThere have been reports of myopathy, rhabdomyolysis, and increased creatine phosphokinase (CPK) levels in patients taking daptomycin, which increased when daptomycin was given more than once per day. designer shoe warehouse mobile alWebOct 5, 2024 · The primary outcome was overall incidence of creatine phosphokinase (CK) elevation, myopathy and rhabdomyolysis. Results and discussion A total of 74 patients who received daptomycin therapy were screened with 50 included in the study. chuck and cheese couponWebDec 13, 2024 · The incidence of rhabdomyolysis was significantly higher following concomitant daptomycin and statin use than with daptomycin alone (OR = 11.60, 95% CI … designer shoe warehouse naperville hoursWebJul 1, 2006 · The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. designer shoe warehouse nearest me