WebResults indicated that circSHOC2 was up-regulated in HG-induced human umbilical vein endothelial cells (HUVECs). Functionally, cellular assays indicated that circSHOC2 silencing repressed... WebDec 1, 2024 · Studies have investigated the neuroprotective effect and mechanisms of circSHOC2 in ischemic preconditioned astrocyte-derived exosomes (IPAS-EXOs) in cerebral ischemia. When astrocytes were deprived of glucose and oxygen for 6 h, circSHOC2 was significantly up-regulated in the exosomes derived from the ischemic …
Frontiers Long Non-coding RNAs and Circular RNAs: Insights Into ...
WebE RNA-binding protein immunoprecipitation (RIP) following PCR assays showed the molecular binding of circSHOC2 and miR-145. F RT-PCR was performed to detect the miR-145 level in high glucose (HG ... WebOct 5, 2024 · CircRNAs are stable in eukaryotic cells. CircRNAs can interact with RNA-binding proteins and modulate mRNA stability, and gene transcription. It is proved that endogenous circRNAs can be translated into proteins ( Chen and Yang, 2015; Meng et al., 2024 ). Moreover, like lncRNAs, circRNAs also have MREs. いらすとや 訪問
Lukui Chen
WebThe aim of the present study was to investigate the neuroprotective roles and mechanisms of the circular RNA circSHOC2 in ischemic-preconditioned astrocyte-derived exosomes (IPAS-EXOs) against... WebApr 1, 2024 · CircSHOC2 significantly upregulated: CircSHOC2/miR-7670-3p/SIRT1 axis: Circshoc2 inhibits neuronal apoptosis and alleviates neuronal damage: Chen W et al. Common RNA-SEQ data of human IS focus tissues and controls: hsa-Circ 0078299 and FXN — Neuroprotection and brain recovery: Silva P W et al. There were 170 AIS … WebOct 18, 2024 · CircSHOC2 (circ_0092670) is transcribed from the SHOC2 gene and shows significantly increased expression in ischemic preconditioning astrocyte exosomes (IPAS-EXOs). SHOC2 is a prototypical leucine-rich repeat protein that promotes downstream receptor tyrosine kinase (RTK)/RAS signaling and plays important roles in several … pa assistant governor